What researchers found was alarming: thinning from Greenland's coast stretched back 200 to 300 kilometers.
"What we see happening at the front reaches far back into the heart of the ice sheet," said first author Shfaqat Abbas Khan in a press release about the study, published in Nature.
"The new model really captures what's going on inland, the old ones do not... you end up with a completely different mass change, or sea level projection," he told AFP in an interview.
The research was conducted at the Northeast Greenland Ice Stream (NEGIS), which covers an estimated 12 percent of Greenland, according to co-author Mathieu Morlighem.
It found that the thinning could add between 13.5 and 15.5 millimeters to sea levels by the end of this century -- equivalent to the entire Greenland ice sheet's contribution during the past 50 years.
"The NEGIS could lose six times more ice than existing climate models estimate," the report found.
Scientists have previously focused on the edges of Greenland's ice sheet to examine active melting as global temperatures rise, largely using satellite data.
One reason for the inland thinning is the intrusion of warm ocean currents, which in 2012 caused the floating extension of the NEGIS to collapse.
That event "has accelerated ice flow and triggered a wave of rapid ice thinning that has spread upstream".
The Greenland ice sheet is currently the main factor in swelling the Earth's oceans, according to NASA, with the Arctic region heating at a faster rate than the rest of the planet.
In a landmark report on climate science last year, the Intergovernmental Panel on Climate Change (IPCC) said the Greenland ice sheet would contribute up to 18 centimeters to sea level rise by 2100 under the highest emissions scenario.
The massive ice sheet, two kilometers thick, contains enough frozen water to lift global seas by over seven meters in total.
Khan said the thinning trend on Greenland's ice sheet will be near impossible to reverse, but can at least be slowed with the right policies in place.
"I really hope that they agree on a reduction on CO2 and as soon as possible," he said in a message to leaders at the COP27 climate talks underway in Egypt.
Earth's surface has warmed, on average, nearly 1.2 degrees Celsius since pre-industrial times, unleashing a catalogue of impacts from heatwaves to more intense storms.
Under the Paris climate deal, countries have agreed to limit warming to well under 2C.
The implications are worrying, as sea level rise already threatens millions of people living along coasts that could find themselves underwater in the decades and centuries to come.