"The medical team that is following Pope Francis has confirmed the Holy Father's discharge" from Rome's Gemelli hospital for Friday, it said in a statement Thursday.
Francis spent the morning Thursday thanking the doctors and nurses who have looked after him during his stay.
He did the rounds in a wheelchair, according to photographs released by the Vatican, and visited children in the pediatric oncology and child neurosurgery department.
Francis underwent a three-hour operation at the Gemelli hospital on June 7.
The pope, who had colon surgery in 2021, had been suffering from a hernia on the site of a scar from a previous surgery.
He was placed under general anaesthesia and the abdominal wall was repaired with a surgical mesh.
All papal audiences have been cancelled until June 18 to give the pontiff time to recover.