Cannabidiol, or CBD, is a non-psychoactive compound derived from cannabis.
The agency wants to know if CBD can be safely eaten every day for a long period or during pregnancy amid concerns about future fertility, Patrick Cournoyer, who heads the FDA office developing the agency's cannabis strategy, told the Wall Street Journal publication.
Cannabis products, excluding Jazz Pharmaceuticals PLC's Epidiolex, are illegal at the federal level in the United States, although some states allow their use.
When asked for comment, the FDA referred Reuters to a statement from last year which said the agency was taking steps to improve regulatory pathways for the lawful marketing of appropriate cannabis and cannabis-derived products.
After weighing the evidence on the compound's safety, the FDA will decide within months how to regulate legal cannabis and whether that will require new agency rules or new legislation from Congress, according to the report.