The incident happened on a road between Ber and Timbuktu, MINUSMA said late Sunday, without identifying the nationalities of those hurt or the state of their injuries.
MINUSMA -- the United Nations Multidimensional Integrated Stabilisation Mission in Mali -- was launched in 2013 to help the impoverished Sahel country cope with a jihadist insurgency.
It is one of the UN's biggest peacekeeping operations, with more than 17,000 troops, police, civilians and volunteers.
It has also suffered the most casualties of any peacekeeping operation.
More than 175 of its members have died in hostile acts.