Abu Agila Mohammad Masud was charged by the United States two years ago for the Lockerbie bombing, in which Americans made up a majority of the victims
After arriving in the United States he was taken to a Justice Department facility in Alexandria, Virginia for initial processing, where his mug shot was taken.
On Monday afternoon at 1800UTC he will appear in federal court in Washington for an initial hearing.
On Sunday Scottish prosecutors announced that he was in American hands, but provided no details how he had been transferred from Libya.
Masud had previously been held in Libya for his alleged involvement in a 1986 attack on a Berlin nightclub.
Only one person has so far been convicted for the bombing of Pan Am flight 103 on December 21, 1988, which remains the deadliest terror attack on British soil.
The bomb on board the Boeing 747, which was flying in December, 1988 from London to New York City, killed all 259 people on board and 11 on the ground, the deadliest ever militant attack in Britain.